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Title: Modulatory potential of Spirulina fusiformis on carcinogen metabolizing enzymes in Swiss albino mice. Author: Mittal A, Kumar PV, Banerjee S, Rao AR, Kumar A. Journal: Phytother Res; 1999 Mar; 13(2):111-4. PubMed ID: 10190182. Abstract: The modulatory potential of Spirulina fusiformis was observed on the hepatic and extrahepatic carcinogen metabolizing enzymes in Swiss albino mice at a dose of 800 mg/kg b.w. given orally. A significant reduction in the hepatic cytochrome P-450 content was observed in the group treated with Spirulina in comparison with the control group. The hepatic glutathione S-transferase activity was induced significantly by Spirulina treatment. There was no change in the extrahepatic glutathione S-transferase activity after the animals were fed with Spirulina.[Abstract] [Full Text] [Related] [New Search]