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  • Title: Tubulointerstitial nephritis associated with minimal self reexposure to rifampin.
    Author: Feinfeld DA, Ansari N, Nuovo M, Hussain A, Mir R.
    Journal: Am J Kidney Dis; 1999 May; 33(5):e3. PubMed ID: 10213665.
    Abstract:
    We report the case of a 27-year-old Asian man who self-medicated with two capsules of rifampin 1 year after completing a continuous course of chemotherapy for tuberculosis that included that drug. He developed flank pain and edema and presented with uremia requiring dialysis; despite this, he had a serum potassium of only 3.5 mEq/L. Renal biopsy showed interstitial infiltrate with inflammation of the tubules. Renal function began to improve after a 3-week course of prednisone. This case is remarkable for the severity of the renal failure despite such a minimal self-exposure.
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