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Title: B-cell (CD79a+) lymphoma affecting the tarsal joint synovia in a sheep. Author: Pearson GR, Day MJ, Main D, Pawade J. Journal: J Comp Pathol; 1999 Apr; 120(3):295-9. PubMed ID: 10213673. Abstract: A lymphoma affecting the synovia was identified in both tarsal joints of an aged sheep. With a panel of cross-reactive antibodies specific for lambda and kappa immunoglobulin light chain, MHC class II, CD3, CD79a and the Ki-67 antigen, the neoplasm was classified as a B-cell lymphoma with uniform expression of surface membrane CD79a. This would seem to be the first report of a lymphoma affecting the synovia in a domestic animal, and the first use of the CD79a reagent on ovine tissue.[Abstract] [Full Text] [Related] [New Search]