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  • Title: Hepatocellular carcinoma.
    Author: Schafer DF, Sorrell MF.
    Journal: Lancet; 1999 Apr 10; 353(9160):1253-7. PubMed ID: 10217098.
    Abstract:
    Hepatocellular carcinoma (HCC) for most patients is a terminal complication of chronic inflammatory and fibrotic liver disease. With regrettably few exceptions, treatment is largely palliative, and long-term survival is rare. However, the major causes of HCC worldwide are known and preventable. Hepatitis B and C exist only in man; the viruses have no known non-human reservoirs. Transmission of the viruses can be interrupted by vaccination against hepatitis B virus infection and improvements in medical techniques for hepatitis C, for which no vaccine has yet been developed.
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