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  • Title: Disulfide bridges are not involved in penicillin-binding protein 1b dimerization in Escherichia coli.
    Author: Chalut C, Remy MH, Masson JM.
    Journal: J Bacteriol; 1999 May; 181(9):2970-2. PubMed ID: 10217796.
    Abstract:
    PBP1b can be found as a dimer in Escherichia coli. Previous results suggested that dimerization involved the cysteine(s) in an intermolecular disulfide bond. We show that either deletion mutants or a mutant without cysteines is fully active and still binds penicillin and that the latter can also form dimers.
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