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  • Title: The effect of furosemide stimulation on renin secretion and its application in examining activity of the renin-angiotensin system.
    Author: Zofková I.
    Journal: Cor Vasa; 1976; 18(4):304-9. PubMed ID: 1022409.
    Abstract:
    The response of plasma renin concentration [PRC] to Furosemide administration and orthostasis stimulation was studied in 9 healthy volunteers and in 30 patients with essential hypertension. The results indicate that Furosemide is unfit for stimulation of renin secretion owing to a relatively high frequency of paradoxical PRC decreases observed both in hypertensives and normotensives. On the other hand, orthostasis stimulation is a manoeuvre suitable also for screening of low renin hypertension.
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