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  • Title: [Microcirculatory changes in the cheek pouch mucosa of hamsters in the dynamics of experimental traumatic shock].
    Author: Shtykhno IuM, Donskikh EA.
    Journal: Biull Eksp Biol Med; 1976 Dec; 82(12):1418-20. PubMed ID: 1023963.
    Abstract:
    Acute experiments conducted on hamsters demonstrated significant disturbances of the microcirculation in the mucosa of the cheek pouch during a severe traumatic shock after a standardized mechanical injury of the hip. All the animals died in the course of the first 24 hours after this trauma. If the animals died not earlier than in one hour after the trauma the microcirculation changes were distinctly phasic in character; particularly there was seen a phase of temporary relative adaptation and stabilization of the peripheral circulation, invariably followed by the phase of decompensation, the terminal phase and death. In cases with a rapid lethal issue in the course of one hour no distinct phasic character of the microcirculation changes was observed, but there was a more or less rapid aggravation of all he indices. In difference from the majority of other investigators, no marked intravascular erythrocyte aggregation was seen by the authors in the experiments described.
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