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  • Title: [Effect of cold exposure on synthesis of cerebral dopamine (author's transl)].
    Author: Beley A, Beley P, Rochette L, Bralet J.
    Journal: J Physiol (Paris); 1976; 72(8):1029-34. PubMed ID: 1025311.
    Abstract:
    The synthesis of dopamine (DA) has been studied in the striatum and cortex of rats exposed to a temperature of 40C for 2.5 or 24 h. The synthesis rate has been estimated 30 mn after an i.v. injection of 3H tyrosine (TY), by the evaluation of the ratio: 3H-DA specific activity 3H-TY specific activity. Cold exposure modified DA synthesis differently in the two brain areas. In the striatum, DA synthesis was multiplied by a factor of 1.5 after 2.5 h of cold exposure and returned to normal value after 24 h. In the cortex, cold exposure did not significantly change DA synthesis (at any of the two times studied).
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