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  • Title: The influence of chemical restraining agents on cardiovascular function: a review.
    Author: Parker JL, Adams HR.
    Journal: Lab Anim Sci; 1978 Oct; 28(5):575-83. PubMed ID: 102871.
    Abstract:
    A review of selected experimental reports indicated that chemical restraining agents commonly used in experimental animals affected basal cardiovascular function and could influence the response of the cardiovascular system to physiologic-pharmacologic stimuli. Drugs that were considered included pentobarbital, halothane, alpha-chloralose, droperidol, fentanyl, and ketamine. In relation to effects on hemodynamics, anesthetic restraint produced by one drug was not necessarily equivalent to that produced by another.
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