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  • Title: [Intensification of cellular immune response by immunization of mice with the cells preincubated in interferon].
    Author: Skurkovich SV, Ol'shanskaia NV, Eremkina EI.
    Journal: Biull Eksp Biol Med; 1976 Oct; 82(10):1230-2. PubMed ID: 1029509.
    Abstract:
    Mice F1(CBA X C57BL/6) were immunized intraperitoneally with a single injection of L-1210 cells preincubated in interferon or control "false" preparation. CBA mice were injected with MX-11 cells: similarly treated according to the same scheme. Injection of interferon-treated cells was accompanied by the enhancement of the cellular immune response. The greatest cytotoxic activity was possessed by the lymphocytes of mice to which M-11 cells were administered together with interferon in which the cells were formerly incubated.
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