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  • Title: Effect of immunosuppressive therapy on the serum glycoprotein levels in chronic aggressive hepatitis.
    Author: Fehér J, Jakab L, Süle I, Tenczer J, Szilvási I, Papp G.
    Journal: Acta Med Acad Sci Hung; 1976; 33(3):207-15. PubMed ID: 1031548.
    Abstract:
    The sera of 24 patients with chronic aggressive hepatitis receiving combined immunosuppressive therapy were studied for the concentrations of the carbohydrate components of glycoproteins and the IgG, IgA, IgM, alpha-2-macroglobulin, coeruloplasmin, beta-1-C-globulin and transferrin levels over a period of 2 years. Liver biopsy was performed repeatedly in 50% of the cases. On the evidence of the results, combined immunosuppressive treatment is regarded as apt to normalize the serum concentrations of IgG, IgA, IgM and to reduce those of alpha-2-macroglobulin and coeruloplasmin. Among the carbohydrate components of glycoproteins only the amount of hexose was reduced.
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