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  • Title: Effect of xanthine oxidase inhibitor on myocardial ischemia.
    Author: Minaga T, Takeda K, Nakamura T, Kizu A, Ijichi H.
    Journal: Recent Adv Stud Cardiac Struct Metab; ; 11():555-8. PubMed ID: 1031953.
    Abstract:
    The xanthine oxidase inhibitor, 4-hydroxypyrazolo(3,4-d) pyrimidine (HPP), Allopurinol, caused augmentation of myocardial uptake of [3H] hypoxanthine, which was eventually completely incorporated into ATP. The decrease of [32P] orthophosphate incorporation into ATP induced by isoproterenol was restored by HPP administration.
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