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  • Title: [The correlation between abusing alcohol and antioxidants, antioxidases].
    Author: Zhou J, Du Y, Wang Y.
    Journal: Zhonghua Yu Fang Yi Xue Za Zhi; 1998 Sep; 32(5):303-5. PubMed ID: 10322779.
    Abstract:
    OBJECTIVE: To study the correlation between abusing alcohol and antioxidants, antioxidases and oxygen free radical reaction. METHODS: We measured spectrophotometrically the plasma vitamin C(P-VC), plasma vitamin E(P-VE), plasma beta-carotene (P-beta-CAR) contents and erythrocyte superoxide dismutase (E-SOD), erythrocyte catalase (E-CAT), erythrocyte glutathione peroxidase (E-GSH-Px) activities in 194 male (40 years old) alcohol abusers and 50 male (40 years old) nondrinkers. RESULTS: The average P-VC, P-VE, P-beta-CAR contents and E-SOD, E-CAT, E-GSH-Px activities of the alcohol abuser group were lower than those of the nondrinker group. The P-VC, P-VE, P-beta-CAR contents and E-SOD, E-CAT, E-GSH-Px activities of the alcohol abusers decreased as the time and quantity of abusing alcohol increased. CONCLUSION: The oxygen free radical reaction in the alcohol abusers was pathologically exacerbated, and the balance between oxidation and antioxidation was serious imbalanced.
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