These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: DNA damage and repair in individual cells: applications of the comet assay in radiobiology.
    Author: Olive PL.
    Journal: Int J Radiat Biol; 1999 Apr; 75(4):395-405. PubMed ID: 10331844.
    Abstract:
    The comet assay is a single-cell gel electrophoresis method that can measure a variety of types of DNA damage, and repair of damage, in individual cells. It is now in widespread use in genetic toxicology and oncology. This review describes the history of the development of this method and its applications in radiation biology, with particular emphasis on the use of the comet assay to measure heterogeneity in DNA damage in cells exposed to ionizing radiation.
    [Abstract] [Full Text] [Related] [New Search]