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  • Title: Cloverleaf skull anomaly with extreme orbitostenosis.
    Author: O'Broin ES, O'Keefe M, Allcutt D, Earley MJ.
    Journal: J Craniofac Surg; 1997 Jan; 8(1):75-7. PubMed ID: 10332303.
    Abstract:
    A neonate presented with cloverleaf skull anomaly and severe proptosis requiring urgent cranioplasty to attain eyelid closure. Despite this, she experienced exposure keratitis and corneal perforations. A ventriculoperitoneal shunt was performed subsequently to relieve hydrocephalus, but respiratory problems eventually led to her death at 6 months. This case highlights the complexity of the problems encountered in the cloverleaf skull anomaly, and a brief review discussing its management is included. Despite improvements in treatment of this condition, the overall prognosis remains poor.
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