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  • Title: Respiratory distress due to minocycline-induced pulmonary lupus.
    Author: Christodoulou CS, Emmanuel P, Ray RA, Good RA, Schnapf BM, Cawkwell GD.
    Journal: Chest; 1999 May; 115(5):1471-3. PubMed ID: 10334177.
    Abstract:
    Minoeycline, a semisynthetic tetracycline, is often used to treat acne and rheumatoid arthritis. It has been considered an unlikely drug to be associated with systemic lupus erythematosus; however, many cases of drug-induced lupus related to minocycline have been reported. Some of those reports included pulmonary lupus, but none of the patients described developed respiratory distress. We describe a patient treated with minocycline for 2 years who presented with progressive dyspnea, severe hypoxia, and pulmonary infiltrates necessitating hospitalization and oxygen supplementation.
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