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  • Title: [Kinetics of proliferation of a mouse tumor cell line originating in the fetal large intestine].
    Author: Khristov K, Argirova R, Urumov I, Boeva M.
    Journal: Eksp Med Morfol; 1976; 15(4):200-6. PubMed ID: 1035158.
    Abstract:
    The authors examine the kinetics of cellular proliferation of the cellular line STS, originating from adenocarcinoma, obtained after "spontaneous" malignization of a fragment from fetal colon. The cells of STS grow as a single layer and reach exponential phase on the 48th hour, but stationary phase-on the 96th hour of the culture. Time for doubling the number of the cells TD at the exponential phase of growth is 12 hours. The mitotic index varies from 7% at the exponential phase to 1,3% at the stationary. Time of cellular cycle and its phases, estimated by the curves of the marked mitosis, shows the following values: TGi=5.3 hours, Ts=6 hours, TG2=0.5 hour, TM=1,2 hour, and TC=13 hours. The authors discuss the differences in the data of TC and TD.
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