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  • Title: Relationship between antidepressant partial and nonresponse and subsequent response to antidepressant augmentation.
    Author: Joffe RT, Levitt AJ.
    Journal: J Affect Disord; 1999; 52(1-3):257-9. PubMed ID: 10357043.
    Abstract:
    OBJECTIVE: To evaluate the relationship between the degree of antidepressant nonresponse and subsequent response to lithium and triiodothyronine (T3) augmentation. METHOD: This is a retrospective analysis of data combined from two previous controlled studies of lithium and triiodothyronine augmentation of tricyclic antidepressants. RESULTS: There was no difference in the rate of augmentation response between partial and nonresponders to tricyclic antidepressant treatment. CONCLUSIONS: Augmentation response does not appear to be related to the degree of nonresponse to the preceding antidepressant trial.
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