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  • Title: Aortic valve replacement in a patient with idiopathic thrombocytopenic purpura.
    Author: Kumamoto T, Higashi S, Sumida T.
    Journal: Jpn J Thorac Cardiovasc Surg; 1999 Apr; 47(4):182-4. PubMed ID: 10358951.
    Abstract:
    A patient with aortic regurgitation and idiopathic thrombocytopenic purpura underwent a successful valve replacement. Cardiac surgery requiring a cardiopulmonary bypass in idiopathic thrombocytopenic purpura can be safely carried out with the preoperative intravenous administration of high-dose gammaglobulin, which may thereby reduce the need for either perioperative transfusion or prophylactic splenectomy.
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