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  • Title: Mutagenic activity of 3,6-diamino-10-methyl-9,10-dihydroacridine in Salmonella typhimurium cells.
    Author: Ferenc T, Janik-Spiechowicz E, Bratkowska W, Denys A.
    Journal: Int J Occup Med Environ Health; 1999; 12(1):67-72. PubMed ID: 10360086.
    Abstract:
    Mutagenic evaluation of 3,6-diamino-10-methyl-9,10-dihydroacridine (AcrH), a new synthesized acridine derivative was undertaken using short-term in vitro test. The mutagenic potential of AcrH was evident from the reverse mutation induced in the presence and absence of S9-mix of Salmonella typhimurium TA97a, TA98, TA100 and TA102 cells. The levels of the mutagenic activity of AcrH in TA97a are comparable with that of acriflavine.
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