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  • Title: Low-frequency damped electroretinographic wavelets in young asymptomatic patients with dominant retinitis pigmentosa: a new electroretinographic finding.
    Author: Lam BL, Liu M, Hamasaki DI.
    Journal: Ophthalmology; 1999 Jun; 106(6):1109-13. PubMed ID: 10366078.
    Abstract:
    OBJECTIVE: To describe a previously unreported electroretinographic (ERG) pattern in early retinitis pigmentosa (RP). DESIGN: Two case reports. PARTICIPANTS: Two unrelated young asymptomatic patients with autosomal-dominant retinitis pigmentosa were studied. MAIN OUTCOME MEASURES: Clinical findings and ERG responses were assessed. RESULTS: No ERG responses were detected scotopically with low-luminance stimuli. With increasingly brighter stimuli, a series of three to five low-frequency damped wavelets developed under both scotopic and photopic conditions. The period of the wavelets was 25 to 37 msec. CONCLUSIONS: Low-frequency damped ERG wavelets occur in some young asymptomatic patients with autosomal-dominant RP. The ERG pattern suggests that these wavelets are predominantly cone-generated.
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