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  • Title: Gastrulation in Drosophila: the logic and the cellular mechanisms.
    Author: Leptin M.
    Journal: EMBO J; 1999 Jun 15; 18(12):3187-92. PubMed ID: 10369659.
    Abstract:
    The egg contains a set of molecules that can be used to trigger cell-shape changes leading to morphogenetic movements. The temporally and spatially controlled activation of these molecules, and hence the choreography of gastrulation movements, is determined by region-specific expression of transcription factors which turn on a set of downstream targets whose products mediate the successive steps of gastrulation.
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