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  • Title: Arteriovenous malformation of the cervical spinal cord in a dog.
    Author: Hayashida E, Ochiai K, Kadosawa T, Kimura T, Umemura T.
    Journal: J Comp Pathol; 1999 Jul; 121(1):71-6. PubMed ID: 10373295.
    Abstract:
    An 8-year-old female German Shepherd dog showed first order Horner's syndrome associated with progressive right-sided hemiplegia and mega-oesophagus. Intramedullary and leptomeningeal arteriovenous malformation (AVM) was identified in the cervical spinal cord. The morphological characteristics were arteriovenous shunting, intramedullary multiple thromboses and haemorrhage, non-inflammatory necrosis of white and grey matter around the shunt, and intervening neural gliosis with neovascularization. These findings suggested that the malformation induced a focal circulatory disturbance within the cervical spinal cord and that fatal thrombosis was responsible for the sudden onset of the nervous signs and progressive neurological deterioration. This is the first report of intramedullary spinal AVM in a dog.
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