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  • Title: [Measurement of urinary content of lactulose and mannitol by gas chromatography as an index of permeability of the gut].
    Author: Zhu X, Xiong D, Sheng Z.
    Journal: Zhonghua Wai Ke Za Zhi; 1997 Apr; 35(4):248-50. PubMed ID: 10374551.
    Abstract:
    We established lactulose-mannitol(L-M) measurement method by gas chromatography and 9202 computer data processing system to test intestinal permeability. The urine output of L-M was in linear correlation to its sample concentration within working range. In an animal model of acute pancreatitis, lactulosesecretion increased in urine, together with increased L/M ratio. The measurement of lactulose-mannitol intestinal permeability by our method might serve as a predictor for early diagnosis of endogenous infection and sepsis.
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