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  • Title: Mutations in catabolite control protein CcpA separating growth effects from catabolite repression.
    Author: Küster E, Hilbich T, Dahl MK, Hillen W.
    Journal: J Bacteriol; 1999 Jul; 181(13):4125-8. PubMed ID: 10383986.
    Abstract:
    Carbon catabolite repression in Bacillus megaterium is mediated by the transcriptional regulator CcpA. A chromosomal deletion of ccpA eliminates catabolite repression and reduces the growth rate on glucose. We describe four single-amino-acid mutations in CcpA which separate the growth effect from catabolite repression, suggesting distinct regulatory pathways for these phenotypes.
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