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  • Title: Use of recombinant human cardiac Troponin T for standardization of third generation Troponin T methods.
    Author: Hallermayer K, Klenner D, Vogel R.
    Journal: Scand J Clin Lab Invest Suppl; 1999; 230():128-31. PubMed ID: 10389211.
    Abstract:
    The Elecsys Troponin T third generation assay uses recombinant human cardiac troponin T as standard material. The new assay has a linear calibration curve. Thus, linearity problems observed with the second generation assay have been eliminated. The assay has high precision, especially at the low end of measuring range (inter-assay CV < 10% at 0.1 microgram/L). The new standardization does not change the cut-off value of 0.1 microgram/L. The use of recombinant human cardiac troponin T as standard material enables a reproducible and reliable standardization of troponin T assays.
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