These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Prandial hypoxia in progressive muscular dystrophy].
    Author: Nakayama T, Ogata K, Ooshiro T, Saito Y, Kawai M.
    Journal: Rinsho Shinkeigaku; 1999 Apr; 39(4):436-40. PubMed ID: 10391969.
    Abstract:
    Progressive muscular dystrophy patients often show progressive body weight loss in early adolescence. This severe body weight loss frequently causes superior mesenteric artery syndrome which may result in a fatal outcome. We performed prandial pulse oximetry and found 12 out of 35 Duchenne muscular dystrophy patients, 1 out of 2 Becker muscular dystrophy patients and 1 out of 3 Limb-Girdle muscular dystrophy patients showed prandial hypoxia with tachycardia. The patients became tired and eating habits were easily interrupted resulting in progressive body weight loss. Nasal administration of 0.2L/min oxygen to 2 Duchenne muscular dystrophy patients, and nasal intermittent positive pressure ventilation to 2 Duchenne muscular dystrophy patients, 1 Becker muscular dystrophy patient and 1 Limb-Girdle muscular dystrophy patient for 15-30 minutes before eating improved the prandial hypoxia and halted the progression of body weight loss. This prandial hypoxia is one of the earliest signs of respiratory failure in progressive muscular dystrophy.
    [Abstract] [Full Text] [Related] [New Search]