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  • Title: mRNA polyadenylation and its coupling to other RNA processing reactions and to transcription.
    Author: Minvielle-Sebastia L, Keller W.
    Journal: Curr Opin Cell Biol; 1999 Jun; 11(3):352-7. PubMed ID: 10395555.
    Abstract:
    Eukaryotic mRNA precursors are processed at their 3' ends by a coupled cleavage/polyadenylation reaction. In recent years, most of the factors involved in 3'-end processing have been identified and evidence has been presented for the coupling of mRNA 3'-end formation to capping, splicing and transcription. These links are important for the quality control of the mRNA during synthesis.
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