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  • Title: [Epidemic of respiratory tract infections by Mycoplasma pneumoniae in an institute for mentally disabled, investigated with polymerase chain reaction of a throat swab specimen].
    Author: Dorigo-Zetsma JW, de Wit M, Szabó JS, Schneeberger PM.
    Journal: Ned Tijdschr Geneeskd; 1999 Jun 12; 143(24):1261-5. PubMed ID: 10396337.
    Abstract:
    OBJECTIVE: To determine the spread of respiratory infection with Mycoplasma pneumoniae in an institute for mentally disabled persons. DESIGN: Descriptive. METHODS: In the period from mid-April to mid-September in a certain year the transmission of M. pneumoniae in the facility was evaluated using questionnaires and laboratory investigations. The laboratory investigations consisted of an M. pneumoniae specific polymerase chain reaction (PCR) on throat swab specimens and detection of antibodies in serum. RESULTS: 21 Residents and 26 staff members from 2/36 units were involved in the initial investigation. 17 Persons had complaints of a (recent) respiratory infection (cough, malaise and fever). In 9 cases an M. pneumoniae infection was confirmed, in 5 cases by PCR and in 4 cases by serology. Two PCR positive persons had only complaints of coughing. During the investigation period 2 more persons were diagnosed with a respiratory infection due to M. pneumoniae. No new cases were found by investigation of contacts outside the facility. CONCLUSION: M. pneumoniae can cause an outbreak of M. pneumoniae respiratory infection in an institute for mentally disabled persons. Rapid detection of this pathogen is possible by PCR and is important for proper antibiotic therapy and epidemic-control measures.
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