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  • Title: An easy stereospecific synthesis of 1-amino-2,5-anhydro-1-deoxy-D-mannitol and arylamino derivatives.
    Author: Claustre S, Bringaud F, Azéma L, Baron R, Périé J, Willson M.
    Journal: Carbohydr Res; 1999 Feb 28; 315(3-4):339-44. PubMed ID: 10399304.
    Abstract:
    1-Amino-2,5-anhydro-1-deoxy-D-mannitol and a series of arylamino derivatives were prepared by nitrous acid deamination of 2-amino-2-deoxy-D-glucose and subsequent reductive amination of the resulting 2,5-anhydro-D-mannose. Some of these compounds showed an enhanced affinity for the hexose transporter of Trypanosoma brucei as compared to D-fructose.
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