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  • Title: Deoxyribonucleoside-requiring mutants of Bacillus subtilis.
    Author: Rima BK, Takahashi I.
    Journal: J Gen Microbiol; 1978 Jul; 107(1):139-45. PubMed ID: 103994.
    Abstract:
    A number of deoxyribonucleoside-requiring mutants (dns) of Bacillus subtilis were isolated and their growth characteristics and ribonucleotide reductase activities were compared with those of the wild type and of a dna mutant (tsA13). Both tsA13 and dns mutants required the presence of a mixture of deoxyribonucleosides for growth at 45 degrees C but not at 25 degrees C. All the mutant strains tested contained ribonucleotide reductase activity which showed heat sensitivity similar to that of the enzyme from a wild-type strain. The reductase in B. subtilis seemed to reduce ribonucleoside triphosphates in a similar manner to the enzyme in Lactobacillus leichmannii.
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