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  • Title: [18F]-labeled 3-deoxy-3-fluoro-D-glucose: synthesis and preliminary biodistribution data.
    Author: Tewson TJ, Welch MJ, Raichle ME.
    Journal: J Nucl Med; 1978 Dec; 19(12):1339-45. PubMed ID: 104019.
    Abstract:
    A cyclotron target system for the production of anhydrous [18F] fluoride ion has been developed and used for the synthesis of carrier-free [18F]-3-deoxy-3fluoro-D-glucose (3-FDG). The synthesis is sufficiently rapid and efficient to allow production of usable amounts of 3-FDG with a 6-MeV cyclotron. Preliminary animal studies show that 3-FDG is in fact a glucose analog.
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