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  • Title: Scleral and episcleral histological changes related to encircling explants in 20 eyes.
    Author: D'Hermies F, Korobelnik JF, Chauvaud D, Pouliquen Y, Parel JM, Renard G.
    Journal: Acta Ophthalmol Scand; 1999 Jun; 77(3):279-85. PubMed ID: 10406146.
    Abstract:
    PURPOSE: To investigate scleral and episcleral histological alterations induced by encircling explants used in scleral buckling procedures. METHODS: We performed a histopathological study of 20 enucleated eyes after failure of retinal detachment surgery including encircling scleral buckle. RESULTS: Nonabsorbable materials were encapsulated and often gave rise to a limited scleral invagination. The inner capsular surface was regular in 10 silicone explants, it was partially covered with hydrogel fragments and a granulomatous foreign body giant cell reaction in 8 hydrogel explants. One Arruga thread was encased in fibrosis and a catgut circle showed no encapsulation. Other changes were mostly related to the long-standing retinal detachment: peripheral anterior synechiae, anterior uveal effusion, persistent retinal detachment, retinal gliosis, retinal atrophy, retinal breaks, and silicone oil droplets. CONCLUSION: All nonabsorbable explants underwent encapsulation and prompted scleral invagination. A granulomatous reaction accompanied hydrogel fragmentation. The long term fragmentation impact on implanted eyes remains unknown.
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