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  • Title: Severe immune hemolytic anemia associated with prophylactic use of cefotetan in obstetric and gynecologic procedures.
    Author: Garratty G, Leger RM, Arndt PA.
    Journal: Am J Obstet Gynecol; 1999 Jul; 181(1):103-4. PubMed ID: 10411803.
    Abstract:
    Second- and third-generation cephalosporins, especially cefotetan, are increasingly associated with severe, sometimes fatal immune hemolytic anemia. We noticed that 10 of our 35 cases of cefotetan-induced hemolytic anemias were in patients who had received cefotetan prophylactically for obstetric and gynecologic procedures. Eight of these cases of severe immune hemolytic anemia are described.
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