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  • Title: Transversal and longitudinal lecithin-sphingomyelin ratios in amniotic and lung fluids of fetal lambs.
    Author: Rethmeier HB, Egberts H.
    Journal: Am J Obstet Gynecol; 1975 Jul 01; 122(5):593-6. PubMed ID: 1041194.
    Abstract:
    Lecithin-sphingomyelin (L/S) ratios were measured in both amniotic and in lung fluids of fetal lambs. Around Day 130 of fetal age sudden increase of L/S ratio appeared in lung fluid. The amniotic L/S ratio increased only slowly as a consequence of which false negative values were obtained. A respiratory distress syndrome is to be expected when the lung fluid shows a L/S ratio less than 2. The L/S ratio of lung fluid is preferable to amniotic L/S ratio. In comparison with those of amniotic fluid the L/S ratios of lung fluid were significantly higher. Lung fluid secretion was measured daily. Large differences were seen among the lambs. Two days before delivery a striking decrease in the quantity of lung fluid production was noticed in all aminals.
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