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  • Title: Nonsteroidal anti-inflammatory activity of 1,2,4-triazolyl-heterocarboxylic derivatives.
    Author: Darias V, Abdala S, Tello ML, Martín Herrera D, Vega S.
    Journal: Arzneimittelforschung; 1999 Jun; 49(6):514-8. PubMed ID: 10417868.
    Abstract:
    A series of 1,2,4-triazolyl-thiophene and 1,2,4-triazolyl-pyrazole carboxylic acid derivatives was tested for acute toxicity and nonsteroidal anti-inflammatory activity. Some of these compounds showed potent analgesic activity and interesting nonsteroidal anti-inflammatory properties in different acute and chronic inflammation models.
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