These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Thyroid disorders associated with interferon treatment in patients with chronic viral hepatitis or multiple sclerosis].
    Author: Diago JI, del Olmo D, Alcázar V, Martínez de Icaya P, Rodríguez E, Martínez Montiel P.
    Journal: Med Clin (Barc); 1999 Jun 19; 113(2):50-1. PubMed ID: 10425619.
    Abstract:
    BACKGROUND: Alpha and beta interferon (IFN-alpha and beta) treatment is associated with the synthesis of thyroid autoantibodies and the development of autoimmune thyroid diseases. METHODS AND RESULTS: We have retrospectively evaluated their effect in patients with chronic viral hepatitis (CH) (n = 118) and multiple esclerosis (ME) (n = 10). Thyroid dysfunction has been detected in 7.4% of patients, and seroconversion in 4.7%. CONCLUSIONS: Pre-treatment antithyroid antibodies do not predispose to altered thyroid function, after IFN therapy; their presence should not contraindicate IFN treatment.
    [Abstract] [Full Text] [Related] [New Search]