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  • Title: Vaccination against Taenia solium cysticercosis in pigs using native and recombinant oncosphere antigens.
    Author: Plancarte A, Flisser A, Gauci CG, Lightowlers MW.
    Journal: Int J Parasitol; 1999 Apr; 29(4):643-7. PubMed ID: 10428641.
    Abstract:
    Pigs were immunised with antigens derived from Taenia solium oncospheres or with a pool of three recombinant antigens from Taenia ovis, and subsequently challenged with T. solium eggs. The native oncosphere antigens induced 83% protection against viable, and 89% protection against the total number of cysticerci established following the challenge infection. Immunisation with the recombinant T. ovis antigens induced 93% protection against the establishment of viable cysticerci, and 74% protection against the total number of cysticerci. These results, and those achieved elsewhere with Taenia saginata and T. ovis, support the possibility of developing a practical vaccine to assist in the control of transmission of T. solium through pigs.
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