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  • Title: Comparison of predictive value for colorectal cancer in subjects with and without rectal bleeding.
    Author: Nakama H, Kayano T, Katsuura T, Kamigaito T, Shimada S, Nishikawa N, Yoshii S, Kamijo N.
    Journal: Hepatogastroenterology; 1999; 46(27):1730-2. PubMed ID: 10430332.
    Abstract:
    BACKGROUND/AIMS: To clarify the association between a sign of rectal bleeding and colorectal cancer, and to reveal the relationship of rectal bleeding to the results of an immunochemical fecal occult blood test. METHODOLOGY: In a population-based cross sectional study, 30,138 subjects who received immunochemical fecal occult blood screening with a 2-day method were divided into two groups, according to the results of a questionnaire on a sign of rectal bleeding, and the positivity rate of an immunochemical occult blood test as well as the predictive value for colorectal cancer were compared in the two groups. RESULTS: The fecal occult blood test was positive in 8.8% of subjects with rectal bleeding and in 6.0% of subjects without rectal bleeding, and the predictive value was 6.4% and 3.3% in subjects with and without rectal bleeding, respectively, showing a significant difference in the positivity rate (p<0.001) as well as the predictive value (p<0.05) between these two groups. CONCLUSIONS: These findings indicate that there are positive relations between the subjects with rectal bleeding presentation and colorectal cancer, and a sign of rectal bleeding and the results of an immunochemical fecal occult blood test.
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