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  • Title: [Non-Hodgkin's lymphoma of the larynx: clinical cases].
    Author: Pisani P, Dosdegani R, Policarpo M, Ramponi A, Gambaro G, Pia F.
    Journal: Acta Otorhinolaryngol Ital; 1999 Apr; 19(2):97-101. PubMed ID: 10434442.
    Abstract:
    Non-Hodgkin Lymphoma (NHL) is a relatively frequent lymphatic system tumor in the head and neck region with both nodal and extranodal localizations. The larynx is one of the least frequent extranodal sites. The present study reports three cases of NHL with extranodal laryngeal localization that had recently come under observation. In these cases, the symptoms reported by the patients were aspecific and not particularly significant. Indirect macroscopic laryngoscopy and direct microlaryngoscopy did not prove pathognomonic while definitive histology clearly diagnosed lymphoma. The treatment of choice for primary laryngeal lymphoma is radiotherapy; combined chemo-radiotherapy is indicated in cases of high malignancy and in multifocal cases.
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