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  • Title: [Early corneal limbal autograft transplantation after alkali burns].
    Author: Chen J, Xu J.
    Journal: Zhonghua Yan Ke Za Zhi; 1997 May; 33(3):233-5. PubMed ID: 10437046.
    Abstract:
    OBJECTIVES: To understand the clinical significance of corneal limbus transplantation on alkali burns. METHODS: 14 New Zealand rabbits were used, 1.0 mol/L NaOH solution was placed on the anterior surface of the eyes for 1 minute. Limbal autograft transplantation was performed on 7 rabbits immediately after the burn. The other 7 rabbits were used as controls. The follow-up period lasted for 1 month and then the histopathological changes of corneas were observed under light and scanning electron microscopes. RESULTS: Faster corneal epithelial healing, less corneal neovascularization and inflammatory cell infiltration occurred in the operative group. CONCLUSIONS: Early limbal autograft transplantation can accelerate corneal epithelial healing, restrain corneal neovascularization and inflammatory response, therefore it can prevent corneal ulceration.
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