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  • Title: [Glucagonoma--somatostatinoma].
    Author: Schusdziarra V.
    Journal: Z Gastroenterol; 1999 Jun; Suppl 1():33-5. PubMed ID: 10444813.
    Abstract:
    Glucagonoma and somatostatinoma are tumors which produce the respective hormone. When these peptides are also secreted into the circulation the clinical syndromes are characterized by the signs and symptoms due to hormone overproduction. In case of the glucagonoma-syndrome diabetes and typical skin lesions are dominating while patients with the somatostatinoma syndrome have diabetes frequently associated with steatorrhea. Surgical resection of the tumor and its metastases as far as possible is the therapy of choice. For symptomatic relief and inhibition of the growth of the metastases interferon-a and somatostatin analogues can be employed.
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