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  • Title: Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D3 receptor antagonist.
    Author: Dubuffet T, Newman-Tancredi A, Cussac D, Audinot V, Loutz A, Millan MJ, Lavielle G.
    Journal: Bioorg Med Chem Lett; 1999 Jul 19; 9(14):2059-64. PubMed ID: 10450981.
    Abstract:
    A new series of benzopyrano[3,4-c]pyrrole derivatives were synthesized and evaluated for their interaction with dopamine D3 versus D2 receptors. Amongst these compounds, 4x (S 33084) was found to be a potent and selective dopamine D3 receptor antagonist.
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