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  • Title: Optical phantom materials for near infrared laser photocoagulation studies.
    Author: Iizuka MN, Sherar MD, Vitkin IA.
    Journal: Lasers Surg Med; 1999; 25(2):159-69. PubMed ID: 10455223.
    Abstract:
    BACKGROUND AND OBJECTIVE: Phantoms were developed that simulate tissue with dynamic and static optical properties with which to study the effects of laser irradiation. STUDY DESIGN/MATERIALS AND METHODS: Albumen, agar, and an absorbing dye (Naphthol Green) were combined to form a phantom with heat sensitive optical properties to mimic tissue response. The optical properties of this phantom were measured by using the added absorber technique. A polyacrylamide phantom with static optical properties was designed with the equivalent values of micro(a) and micro'(s) by combining appropriate concentrations of Naphthol Green and Intralipid-10%. RESULTS: The absorption and reduced scattering coefficient of the phantoms were 0. 50 +/- 0.04 cm(-1) and 2.67 +/- 0.07 cm(-1) respectively, in the native state at 805 nm. In the coagulated state, the absorption and scattering coefficient were 0.7 +/- 0.1 cm(-1) and 13.1 +/- 0.5 cm(-1) respectively. CONCLUSION: Two phantoms with dynamic or static optical properties were developed with properties similar to tissue. They may be used in future studies of opto-thermal effects in tissues.
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