These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Membrane lipids of brush border of the rat small intestine as affected by ionizing radiation].
    Author: Stepanova LI, Stepanov IuV, Voĭtsits'kyĭ VM, Kucherenko ME.
    Journal: Ukr Biokhim Zh (1999); 1999; 71(1):48-52. PubMed ID: 10457990.
    Abstract:
    It was established that single total X-ray irradiation in the doses of 0.1; 0.4; 1.0; 2.0; 3.0 and 6.0 Gy 24 hours after irradiation results in reliable changes in membrane lipids composition of brush border of enterocytes in doses over 1.0 Gy. By this changes under increase of dosage of irradiation it were marked differences in comparison with control in lipid-protein, total phospholipids-protein, cholesterol-protein and cholesterol-total phospholipids rations. In lipid composition major changes are connected with increase of lysophosphatidylcholine and lysophosphatidylethanolamine concentrations, decrease of sphingomyelin content and increase of that of phosphatidylethanolamine. Content of cholesterol and free fatty acids decreased reliably under irradiation in doses over 1.0 Gy as well. Data obtained proves that structural-functional properties of brush border membranes of enterocytes of small intestine are altered under irradiation in doses ranging from 1.0 to 6.0 Gy. Lower doses (0.1; 0.4) cause only trend of changes named above.
    [Abstract] [Full Text] [Related] [New Search]