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  • Title: [Critical appraisal of treatments in emergency settings].
    Author: Takahashi H, Takezawa J, Fukuoka T, Mayumi T.
    Journal: Nihon Geka Gakkai Zasshi; 1999 Jul; 100(7):449-54. PubMed ID: 10481851.
    Abstract:
    A critical appraisal was carried out of treatment with high-dose epinephrine (HDE) in cardiopulmonary resuscitation (CPR), active compression and decompression CPR (ACD-CPR), military antishock trousers (MAST), and Continuous renal replacement therapy (CRRT) in the emergency setting, based on evidence-based medicine. Although the pathophysiological rationale encourage the clinical application of these treatments to improve the long-term outcome (mortality), no clinical trial could confirm their benefit. Additionally, Japanese investigators have reported no clinical epidemiological study related to this issue. Thus a clinicoepidemiological study associated with treatments in critical settings is required in this country.
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