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Pubmed for Handhelds

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  • Title: Demonstration of HPV 24 in long-standing Heck's disease with malignant transformation.
    Author: Niebrügge B, Villiers E, Gerlach K, Franke I, Gollnick H.
    Journal: Eur J Dermatol; 1999 Sep; 9(6):477-9. PubMed ID: 10491507.
    Abstract:
    We report on the rare case of a 64-year-old European woman with a viral acanthoma of the oral mucosa of the clinical Heck type with unprecedented molecular-biological proof of HPV 24 DNA and so far undescribed malignant transformation with a long existence of the vegetation. After surgical therapy a circumscribed relapse of viral acanthoma developed, which responded favourably to a combined antiviral and antiproliferative therapy with acitretin perorally and interferon, first subcutaneously, later intralesionally for 3 months.
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