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  • Title: The medullary collecting duct urea transporters.
    Author: Sands JM.
    Journal: Curr Opin Nephrol Hypertens; 1999 Jul; 8(4):499-504. PubMed ID: 10491746.
    Abstract:
    The terminal inner medullary collecting duct facilitated urea transporter, UT-A1, belongs to a family of four urea transporters. The inner medullary collecting duct also expresses three active urea transporters. Reducing urine concentrating ability in vivo upregulates UT-A1 and alters active urea secretion in the terminal inner medullary collecting duct, and induces active urea reabsorption in the initial inner medullary collecting duct.
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