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  • Title: Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase.
    Author: Greenlee ML, Laub JB, Balkovec JM, Hammond ML, Hammond GG, Pompliano DL, Epstein-Toney JH.
    Journal: Bioorg Med Chem Lett; 1999 Sep 06; 9(17):2549-54. PubMed ID: 10498206.
    Abstract:
    Potent thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase have been synthesized employing a solid-phase Mitsunobu reaction as the key step.
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