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  • Title: [Sublingual thyroid gland associated with polycystic ovaries].
    Author: Forsbach G, Galache-Vega P, Hernández-Ayup S.
    Journal: Ginecol Obstet Mex; 1999 Aug; 67():367-9. PubMed ID: 10504788.
    Abstract:
    OBJECTIVE: To describe a young woman with polycystic ovary syndrome and a lingual thyroid gland. CLINICAL HISTORY: A 19-year old woman with secondary amenorrhea whose previous history had been uneventful. She had a normal spontaneous puberty with menarche at 13 years, followed by cyclical menstruations until six months before, when a period of four months of amenorrhea occurred. Physical exploration disclosed a normal young adult woman, without goiter, galactorrhea, acne, nor hirsutism. A pelvic ultrasound showed bilateral enlargement of the ovaries. Hormonal studies showed FSH 4 mUl/mL (nl = 2-12), LH 6 mUl/mL (nl = 2-14) and PRL 12 ng/mL (nl = < 25); TSH 8 microU/mL (nl < 5) and a free thyroxine level of 8.4 ng/dl (nl = 0.75-1.8). A thyroid gammagram with radioiodine disclosed a 6% caption (nl = 8.15%) and a small nodular gland at the base of the tongue. TREATMENT: Levothyroxine 100 micrograms/day was initiated and a month later the TSH level was normal but cyclical menstruations were not established after six months of follow up. COMMENT: The polycystic ovary syndrome is the main endocrine cause of secondary amenorrhea in young women.
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